The vehicle and low dose groups exhibited no signs of toxicity. The mid level group showed mild to moderate signs of toxicity manifesting as an altered gait and lack of grooming in 3 of the 10 rats of each sex. The high dose group showed moderate signs of toxicity manifesting as an altered gait and lack of grooming in 5 of the 10 rats. Three rats (2 male, 1 female) from group 2 and 4 rats from group 1 (2 male, 2 female) were found to exhibit severe signs of toxicity and were euthanized between 19th and 24th day of dosing. These rats also experienced a loss in body weight of 5% per day for three days. Blood was collected from these rats and all clinical hematology and biochemistry performed. The change in daily body weight decreased in animals on the higher dose compared to rat administered vehicle or lower doses of the test item.
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The vehicle and low dose groups exhibited no signs of toxicity. The mid level group showed mild to moderate signs of toxicity manifesting as an altered gait and lack of grooming in 3 of the 10 rats of each sex. The high dose group showed moderate signs of toxicity manifesting as an altered gait and lack of grooming in 5 of the 10 rats. Three rats (2 male, 1 female) from group 2 and 4 rats from group 1 (2 male, 2 female) were found to exhibit severe signs of toxicity and were euthanized between 19th and 24th day of dosing. These rats also experienced a loss in body weight of 5% per day for three days. Blood was collected from these rats and all clinical hematology and biochemistry performed. The change in daily body weight decreased in animals on the higher dose compared to rat administered vehicle or lower doses of the test item.
Why Work with Us
Top Quality and Well-Researched Papers
We always make sure that writers follow all your instructions precisely. You can choose your academic level: high school, college/university or professional, and we will assign a writer who has a respective degree.
Professional and Experienced Academic Writers
We have a team of professional writers with experience in academic and business writing. Many are native speakers and able to perform any task for which you need help.
Free Unlimited Revisions
If you think we missed something, send your order for a free revision. You have 10 days to submit the order for review after you have received the final document. You can do this yourself after logging into your personal account or by contacting our support.
Prompt Delivery and 100% Money-Back-Guarantee
All papers are always delivered on time. In case we need more time to master your paper, we may contact you regarding the deadline extension. In case you cannot provide us with more time, a 100% refund is guaranteed.
Original & Confidential
We use several writing tools checks to ensure that all documents you receive are free from plagiarism. Our editors carefully review all quotations in the text. We also promise maximum confidentiality in all of our services.
24/7 Customer Support
Our support agents are available 24 hours a day 7 days a week and committed to providing you with the best customer experience. Get in touch whenever you need any assistance.
Try it now!
How it works?
Follow these simple steps to get your paper done
Place your order
Fill in the order form and provide all details of your assignment.
Proceed with the payment
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Receive the final file
Once your paper is ready, we will email it to you.
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No need to work on your paper at night. Sleep tight, we will cover your back. We offer all kinds of writing services.
Essays
No matter what kind of academic paper you need and how urgent you need it, you are welcome to choose your academic level and the type of your paper at an affordable price. We take care of all your paper needs and give a 24/7 customer care support system.
Admissions
Admission Essays & Business Writing Help
An admission essay is an essay or other written statement by a candidate, often a potential student enrolling in a college, university, or graduate school. You can be rest assurred that through our service we will write the best admission essay for you.
Reviews
Editing Support
Our academic writers and editors make the necessary changes to your paper so that it is polished. We also format your document by correctly quoting the sources and creating reference lists in the formats APA, Harvard, MLA, Chicago / Turabian.
Reviews
Revision Support
If you think your paper could be improved, you can request a review. In this case, your paper will be checked by the writer or assigned to an editor. You can use this option as many times as you see fit. This is free because we want you to be completely satisfied with the service offered.