The genetics aspect of the disease has established that Tay-Sachs is a genetic disorder caused by a recessive autosomal gene where parents who have the disease-causing gene increase the chances of having a child with Tay-Sachs. Autosomal genes exist in every human being and any mutations that exist in this gene are passed on to the child. To determine whether parents are carrying a mutation in the autosomal gene, the Mendelian ratio is used to determine whether there is a 25% chance of the child suffering from Tay-Sachs. In the genetic diagnosis of the disease, physicians normally use an ophthalmoscope to detect the presence of macula which is a common symptom of the disease (Moe & Benke, 2005).
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