The endoderm and the ectoderm are the tissues in which the teeth originate in most vertebrates through a process of invagination. Some teeth also have a mixed origin of both the ectoderm and ectoderm. The tooth creating capacity of neural crest cells of the ectoderm and the endoderm are therefore the major factor that influenced evolution of teeth rather than the epithelial tissues(3). Mutations in the genome of ancient fish are the factors that resulted in the invasion of the odontodes into the mouth cavity. The development of different phenotypes of vertebrate teeth resulted from Mutations in the genome of ancient vertebrates through years of evolution. The process of teeth like projections on the body of vertebrates evolving into teeth is clear in some type of sharks where the scales present on the body of the shark change to form teeth in their mouth cavity. The dietary habits and other ecological adaptations made the vertebrates teeth to evolve into many physiological shapes like canines, molars, premolars and incisors (4)
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