DNA methylation emerges later in life

Evidence using the MZ twins has revealed that a difference in DNA methylation emerges later in life, suggesting an environmental rather than a genetic basis for the lifelong DNA methylation drift (Fraga et al., 2005).

Thus, it is possible that environmental exposures, which would affect the activity of the methylation machinery, would also lead to behavioral and mental pathologies. Future studies should now address the specific mechanisms responsible for the observed epigenetic drift of MZ twins. Such studies can provide key insight regarding the impact of environment-gene interaction on behavior and vulnerability to disease over the lifespan. In conclusion, it is likely that epigenetic patterns translate or at least contribute to the relationship between the environment and human health (Mathews and Janusek, 2011)

Don't use plagiarized sources. Get Your Custom Essay on
DNA methylation emerges later in life
Just from $13/Page
Order Essay

The study of epigenetic profiles in twins offers an excellent opportunity to understand the causes and consequences of epigenetic variation. The contribution of epigenetic variants to complex phenotypes can be assessed using disease-discordant MZ twins who are otherwise matched for genetics, age, sex, cohort effects, maternal effects and a common environment. These twin designs are considerably more powerful discovery tools than studies on singletons. In the near future, large-scale epigenetic studies in twins across different ages, tissues, and diseases will improve our understanding of the etiology and mechanisms of a wide range of common complex traits and diseases (Bell and Spector, 2011).

However, there are several limitations in regards to the investigation of how MZ twins are phenotypically different from one another. Researchers need to analyze hundreds of identical MZ twin pairs, control the manipulation of the environment, and obtain numerous samples of tissue and or genes at several time points across the lifespan. Additionally, researchers need to look at several generations of MZ twins. All thses limitations may not be feasible in human; therefore, laboratory animals could provide a venue to address complex research questions while controlling confounding variable of the environmental factors as much as possible (Carey, 2011)

Assignment Help Guys
Calculate your paper price
Pages (550 words)
Approximate price: -

Why Work with Us

Top Quality and Well-Researched Papers

We always make sure that writers follow all your instructions precisely. You can choose your academic level: high school, college/university or professional, and we will assign a writer who has a respective degree.

Professional and Experienced Academic Writers

We have a team of professional writers with experience in academic and business writing. Many are native speakers and able to perform any task for which you need help.

Free Unlimited Revisions

If you think we missed something, send your order for a free revision. You have 10 days to submit the order for review after you have received the final document. You can do this yourself after logging into your personal account or by contacting our support.

Prompt Delivery and 100% Money-Back-Guarantee

All papers are always delivered on time. In case we need more time to master your paper, we may contact you regarding the deadline extension. In case you cannot provide us with more time, a 100% refund is guaranteed.

Original & Confidential

We use several writing tools checks to ensure that all documents you receive are free from plagiarism. Our editors carefully review all quotations in the text. We also promise maximum confidentiality in all of our services.

24/7 Customer Support

Our support agents are available 24 hours a day 7 days a week and committed to providing you with the best customer experience. Get in touch whenever you need any assistance.

Try it now!

Calculate the price of your order

Total price:

How it works?

Follow these simple steps to get your paper done

Place your order

Fill in the order form and provide all details of your assignment.

Proceed with the payment

Choose the payment system that suits you most.

Receive the final file

Once your paper is ready, we will email it to you.

Our Services

No need to work on your paper at night. Sleep tight, we will cover your back. We offer all kinds of writing services.


Essay Writing Service

No matter what kind of academic paper you need and how urgent you need it, you are welcome to choose your academic level and the type of your paper at an affordable price. We take care of all your paper needs and give a 24/7 customer care support system.


Admission Essays & Business Writing Help

An admission essay is an essay or other written statement by a candidate, often a potential student enrolling in a college, university, or graduate school. You can be rest assurred that through our service we will write the best admission essay for you.


Editing Support

Our academic writers and editors make the necessary changes to your paper so that it is polished. We also format your document by correctly quoting the sources and creating reference lists in the formats APA, Harvard, MLA, Chicago / Turabian.


Revision Support

If you think your paper could be improved, you can request a review. In this case, your paper will be checked by the writer or assigned to an editor. You can use this option as many times as you see fit. This is free because we want you to be completely satisfied with the service offered.

error: Content is protected !!
Open chat
Need assignment help? You can contact our live agent via WhatsApp using +1 718 717 2861

Feel free to ask questions, clarifications, or discounts available when placing an order.